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§331. Prohibited acts — Lineage

21 U.S.C. § 331

How 21 U.S.C. § 331 came to say what it says — from its enactment, through every amendment and release point, to the regulations that draw authority from it.

How this provision came to be

  1. Dec 29, 2022 Amendment Pub. L. 117–328 — Modernization of Cosmetics Regulation Act of 2022 See what changed
  2. Oct 24, 2018 Amendment Pub. L. 115–271 — Stop Illicit Drug Importation Act of 2018 See what changed
  3. Dec 13, 2016 Amendment Pub. L. 114–255 — 21st Century Cures Act See what changed
  4. Dec 28, 2015 Amendment Pub. L. 114–114 — Microbead-Free Waters Act of 2015 See what changed
  5. Nov 27, 2013 Amendment Pub. L. 113–54 — Drug Supply Chain Security Act See what changed
  6. Jul 9, 2012 Amendment Pub. L. 112–144 — Biosimilar User Fee Act of 2012 See what changed
  7. Jan 4, 2011 Amendment Pub. L. 111–353 — FDA Food Safety Modernization Act See what changed
  8. Jun 22, 2009 Amendment Pub. L. 111–31 — Family Smoking Prevention and Tobacco Control Act See what changed
  9. Sep 27, 2007 Amendment Pub. L. 110–85 — Best Pharmaceuticals for Children Act of 2007 See what changed
  10. Dec 22, 2006 Amendment Pub. L. 109–462 — Dietary Supplement and Nonprescription Drug Consumer Protection Act See what changed
  11. Aug 10, 2005 Amendment Pub. L. 109–59 — Sanitary Food Transportation Act of 2005 See what changed
  12. Aug 2, 2004 Amendment Pub. L. 108–282 — Minor Use and Minor Species Animal Health Act of 2004 See what changed
  13. Apr 1, 2004 Amendment Pub. L. 108–214 — Medical Devices Technical Corrections Act See what changed
  14. Dec 8, 2003 Amendment Pub. L. 108–173 — Medicare Prescription Drug, Improvement, and Modernization Act of 2003 See what changed
  15. Nov 24, 2003 Amendment Pub. L. 108–136 — Services Acquisition Reform Act of 2003 See what changed
  16. Oct 26, 2002 Amendment Pub. L. 107–250 — Medical Device User Fee and Modernization Act of 2002 See what changed
  17. Jun 12, 2002 Amendment Pub. L. 107–188 — Agricultural Bioterrorism Protection Act of 2002 See what changed
  18. Oct 28, 2000 Amendment Pub. L. 106–387 — Medicine Equity and Drug Safety Act of 2000 See what changed
  19. Nov 21, 1997 Amendment Pub. L. 105–115 — Food and Drug Administration Modernization Act of 1997 See what changed
  20. Oct 9, 1996 Amendment Pub. L. 104–250 — Animal Drug Availability Act of 1996 See what changed
  21. Aug 3, 1996 Amendment Pub. L. 104–170 — Food Quality Protection Act of 1996 See what changed
  22. Apr 26, 1996 Amendment Pub. L. 104–134 — FDA Export Reform and Enhancement Act of 1996 See what changed
  23. Oct 25, 1994 Amendment Pub. L. 103–417 — Dietary Supplement Health and Education Act of 1994
  24. Oct 22, 1994 Amendment Pub. L. 103–396 — Animal Medicinal Drug Use Clarification Act of 1994
  25. Aug 13, 1993 Amendment Pub. L. 103–80 — Nutrition Labeling and Education Act Amendments of 1993
  26. Oct 29, 1992 Amendment Pub. L. 102–571 — Prescription Drug User Fee Act of 1992
  27. Jun 16, 1992 Amendment Pub. L. 102–300 — Medical Device Amendments of 1992
  28. Nov 5, 1990 Amendment Pub. L. 101–508 — Student Loan Default Prevention Initiative Act of 1990
  29. Nov 3, 1990 Amendment Pub. L. 101–502 — Vaccine and Immunization Amendments of 1990
  30. Apr 22, 1988 Amendment Pub. L. 100–293 — Prescription Drug Marketing Act of 1987
  31. Oct 27, 1986 Amendment Pub. L. 99–570 — Alcohol and Drug Abuse Amendments of 1986
  32. Sep 26, 1980 Amendment Pub. L. 96–359 — Infant Formula Act of 1980
  33. May 28, 1976 Amendment Pub. L. 94–295 — Medical Device Amendments of 1976
  34. Aug 16, 1972 Amendment Pub. L. 92–387 — Drug Listing Act of 1972
  35. Oct 27, 1970 Amendment Pub. L. 91–513 — Controlled Substances Act
  36. Oct 24, 1968 Amendment Pub. L. 90–639
  37. Jul 13, 1968 Amendment Pub. L. 90–399 — Animal Drug Amendments of 1968
  38. Jul 15, 1965 Amendment Pub. L. 89–74 — Drug Abuse Control Amendments of 1965
  39. Oct 10, 1962 Amendment Pub. L. 87–781 — Drug Amendments of 1962
  40. Jul 12, 1960 Amendment Pub. L. 86–618 — Color Additive Amendments of 1960
  41. Sep 6, 1958 Amendment Pub. L. 85–929 — Food Additives Amendment of 1958
  42. Aug 7, 1953 Amendment Act of Aug. 7, 1953, ch. 350
  43. Mar 16, 1950 Amendment Act of Mar. 16, 1950, ch. 61
  44. Jun 24, 1948 Amendment Act of June 24, 1948, ch. 613
  45. Mar 10, 1947 Amendment Act of Mar. 10, 1947, ch. 16
  46. Jul 6, 1945 Amendment Act of July 6, 1945, ch. 281
  47. Dec 22, 1941 Amendment Act of Dec. 22, 1941, ch. 613
  48. Transfer of Functions
  49. Jun 25, 1938 Enacted Act of June 25, 1938, ch. 675

Release history

28 of 402 release points changed the text.

  1. reading now Public Law 119-102 Text changed See what changed
  2. 58 release points — no change to the text
  3. 20 release points — no change to the text
  4. 45 release points — no change to the text
  5. 7 release points — no change to the text
  6. 53 release points — no change to the text
  7. 31 release points — no change to the text
  8. 71 release points — no change to the text
  9. 27 release points — no change to the text
  10. 50 release points — no change to the text
  11. 5 release points — no change to the text
  12. 2 release points — no change to the text
  13. Jan 15, 2013 Public Law 112-283 Text changed See what changed
  14. Jan 3, 2012 Public Law 112-90
  15. Jan 7, 2011 Public Law 111-383 Text changed See what changed
  16. Feb 1, 2010 Public Law 111-137 Text changed See what changed
  17. Jan 5, 2009 Public Law 110-460
  18. Jan 8, 2008 Public Law 110-180 Text changed See what changed
  19. Jan 3, 2007 Public Law 109-482 Text changed See what changed
  20. Jan 2, 2006 Public Law 109-173 Text changed See what changed
  21. Jan 3, 2005 Public Law 108-498 Text changed See what changed
  22. Jan 19, 2004 Public Law 108-198 Text changed See what changed
  23. Jan 6, 2003 Public Law 107-377 Text changed See what changed
  24. Jan 22, 2002 Public Law 107-136 Text changed See what changed
  25. Jan 2, 2001 Public Law 106-580 Text changed See what changed
  26. 2 release points — no change to the text
  27. Jan 26, 1998 Public Law 105-153 Text changed See what changed
  28. Jan 6, 1997 Public Law 104-333 Text changed See what changed
  29. Jan 16, 1996 Public Law 104-98
  30. Jan 4, 1995 Public Law 103-465 Text changed

Derived authority

Named as rulemaking authority in 288 regulations.

and 282 more →