---
kind: "section"
citation: "21 C.F.R. § 558.485"
title: "21"
number: "558.485"
heading: "Pyrantel."
url: "https://uscodex.org/cfr/21/558.485"
---

# §558.485. Pyrantel.

- (a) **Specifications.** Type A medicated articles containing 48 or 80 grams per pound pyrantel tartrate.
- (b) **Sponsors.** See sponsors in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter for use as follows:
  - (1) **No.** 066104: 48 and 80 grams per pound for use as in [paragraph (e)(1)](#e-1) of this section.
  - (2) **Nos.** 017135 and 054771: 48 grams per pound for use as in [paragraph (e)(2)](#e-2) of this section.
- (c) **Related tolerances.** See [§ 556.560](/cfr/21/556.560.md) of this chapter.
- (d) **Special considerations.**
  - (1) See [§ 500.25](/cfr/21/500.25.md) of this chapter. Consult a veterinarian before using in severely debilitated animals.
  - (2) **Do not mix in Type B or Type C medicated feeds containing bentonite.**
- (e) **Conditions of use—**
  - (1) **Swine—**
  - (2) **Horses—**
    - (ii) **Top dress medicated feed—**
      - (A) **Proprietary Formulas.** The following feed can be manufactured only per an approved proprietary formula and specifications:
      - (B) [Reserved]
  - (3) Pyrantel may also be used in combination with:
    - (i) Carbadox as in [§ 558.115](/cfr/21/558.115.md).
    - (ii) Lincomycin as in [§ 558.325](/cfr/21/558.325.md).
    - (iii) Tylosin as in [§ 558.625](/cfr/21/558.625.md).

## Notes

### Amendments

[83 FR 48948, Sept. 28, 2018, as amended at 83 FR 64744, Dec. 18, 2018; 86 FR 14826, Mar. 19, 2021; 89 FR 42360, May 15, 2024]

### Authority

Authority: 21 U.S.C. 354, 360b, 360ccc, 360ccc-1, 371.

### Source

Source: 40 FR 13959, Mar. 27, 1975, unless otherwise noted.

### Amendments

[83 FR 48948, Sept. 28, 2018, as amended at 83 FR 64744, Dec. 18, 2018; 86 FR 14826, Mar. 19, 2021; 89 FR 42360, May 15, 2024]